Zhao, Guisen: search on Z-Library

Fundraising September 15, 2024 – October 1, 2024 About fundraising

The world's largest scientific articles store. 70,000,000+ articles for free.

Fundraising September 15, 2024 – October 1, 2024

Z-Library is one of the largest online libraries in the world that contains over 17,000,000 books and 84,837,000 articles. We aim to make literature accessible to everyone. Today (September 15, 2024) we've started additional fundraising to project maintenance and development.

Also UNLIMITED downloads (for 31 days after the day of making donation) are available for ALL contributors who will donate during the fundraising period till October 1, 2024.

About fundraisingRead more

Make a donation

1

Developments in Nonsteroidal Antiandrogens Targeting the Androgen Receptor

Bo Liu, Lei Su, Jingkun Geng, Junjie Liu, Prof. Guisen Zhao

Journal:

Year:

2010

Language:

english

File:

PDF, 488 KB

english, 2010

2

Study on the application of parent-of-origin specific DNA methylation markers to forensic genetics

Guisen Zhao, Qingen Yang, Daixin Huang, Chunying Yu, Rongzhi Yang, Hui Chen, Kun Mei

Journal:

Forensic Science International

Year:

2005

Language:

english

File:

PDF, 146 KB

english, 2005

3

Targeting Bruton's tyrosine kinase for the treatment of B cell associated malignancies and autoimmune diseases: Preclinical and clinical developments of small molecule inhibitors

Zhang, Zhen, Zhang, Daoguang, Liu, Yang, Yang, Dezhi, Ran, Fansheng, Wang, Michael L., Zhao, Guisen

Journal:

Archiv der Pharmazie

Year:

2018

Language:

english

File:

PDF, 2.30 MB

english, 2018

4

Virtual Observation Method and Precision Estimation for Ill-Posed Partial EIV Model

Wang, Leyang, Wen, Guisen, Zhao, Yingwen

Journal:

Journal of Surveying Engineering

Year:

2019

Language:

english

File:

PDF, 575 KB

english, 2019

5

ChemInform Abstract: Developments in Nonsteroidal Antiandrogens Targeting the Androgen Receptor

Bo Liu, Lei Su, Jingkun Geng, Junjie Liu, Guisen Zhao

Journal:

Year:

2011

File:

PDF, 20 KB

2011

6

Synthesis and structure–activity relationship of ethacrynic acid analogues on glutathione-s-transferase P1-1 activity inhibition

Guisen Zhao, Tao Yu, Rui Wang, Xiaobing Wang, Yongkui Jing

Journal:

Bioorganic & Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 291 KB

english, 2005

7

The synthesis of α,β-unsaturated carbonyl derivatives with the ability to inhibit both glutathione S-transferase P1-1 activity and the proliferation of leukemia cells

Guisen Zhao, Chuan Liu, Rui Wang, Dandan Song, Xiaobing Wang, Hongxiang Lou, Yongkui Jing

Journal:

Bioorganic & Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 249 KB

english, 2007

8

Amide-containing diketoacids as HIV-1 integrase inhibitors: Synthesis, structure–activity relationship analysis, and biological activity

Hongcai Li, Chao Wang, Tino Sanchez, Yanmei Tan, Chunying Jiang, Nouri Neamati, Guisen Zhao

Journal:

Bioorganic & Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 559 KB

english, 2009

9

Design and synthesis of novel nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors from caffeic acid phenethyl ester

Peng Wang, Chuan Liu, Tino Sanches, Yuan Zhong, Bo Liu, Junlong Xiong, Nouri Neamati, Guisen Zhao

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2009

Language:

english

File:

PDF, 541 KB

english, 2009

10

The synthesis of ethacrynic acid thiazole derivatives as glutathione S-transferase pi inhibitors

Ting Li, Guyue Liu, Hongcai Li, Xinmei Yang, Yongkui Jing, Guisen Zhao

Journal:

Bioorganic & Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 239 KB

english, 2012

11

Inhibition of Na,K-ATPase Activates PI3 Kinase and Inhibits Apoptosis in LLC-PK1 Cells

Xiaoming Zhou, Guisen Jiang, Aiping Zhao, Tzvetanka Bondeva, Przemyslaw Hirszel, Tamas Balla

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 182 KB

english, 2001

12

Thiadiazole-a Promising Structure in Medicinal Chemistry

Li, Yijing, Geng, Jingkun, Liu, Yang, Yu, Shenghui, Zhao, Guisen

Journal:

Year:

2013

Language:

english

File:

PDF, 567 KB

english, 2013

13

Synthesis and Biological Investigation of Coumarin Piperazine (Piperidine) Derivatives as Potential Multireceptor Atypical Antipsychotics

Chen, Yin, Wang, Songlin, Xu, Xiangqing, Liu, Xin, Yu, Minquan, Zhao, Song, Liu, Shicheng, Qiu, Yinli, Zhang, Tan, Liu, Bi-Feng, Zhang, Guisen

Journal:

Journal of Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 935 KB

english, 2013

14

Design and synthesis of novel pyrimidone analogues as HIV-1 integrase inhibitors

Yu, Shenghui, Sanchez, Tino Wilson, Liu, Yang, Yin, Yanzhen, Neamati, Nouri, Zhao, Guisen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 571 KB

english, 2013

15

Synthesis and biological evaluation of a series of benzoxazole/benzothiazole-containing 2,3-dihydrobenzo[b][1,4]dioxine derivatives as potential antidepressants

Wang, Songlin, Chen, Yin, Zhao, Song, Xu, Xiangqing, Liu, Xin, Liu, Bi-Feng, Zhang, Guisen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2014

Language:

english

File:

PDF, 840 KB

english, 2014

16

Design, synthesis and evaluation of novel indole derivatives as AKT inhibitors

Yang, Dezhi, Wang, Peng, Liu, Jianzhen, Xing, Hualu, Liu, Yang, Xie, Wencheng, Zhao, Guisen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 2.28 MB

english, 2014

17

The unusual variations of photoluminescence and afterglow properties in monoclinic ZrO2 by annealing

Wang, Zhilong, Zhang, Jiachi, Zheng, Guisen, Liu, Yongqi, Zhao, Yali

Journal:

Journal of Luminescence

Year:

2012

Language:

english

File:

PDF, 759 KB

english, 2012

18

Design and discovery of 5-hydroxy-6-oxo-1,6-dihydropyrimidine-4-carboxamide inhibitors of HIV-1 integrase

Zhang, Daoguang, Debnath, Bikash, Yu, Shenghui, Sanchez, Tino Wilson, Christ, Frauke, Liu, Yang, Debyser, Zeger, Neamati, Nouri, Zhao, Guisen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 1.10 MB

english, 2014

19

Nitrogen-containing polyhydroxylated aromatics as HIV-1 integrase inhibitors: synthesis, structure-activity relationship analysis, and biological activity

Yu, Shenghui, Zhang, Linna, Yan, Shifeng, Wang, Peng, Sanchez, Tino, Christ, Frauke, Debyser, Zeger, Neamati, Nouri, Zhao, Guisen

Journal:

Journal of Enzyme Inhibition and Medicinal Chemistry

Year:

2012

Language:

english

File:

PDF, 1.03 MB

english, 2012

20

Methyl 4-benzyloxy-7-methoxy-1-methyl-1 H -indole-2-carboxylate

Wang, Peng, Xing, Hualu, Liu, Yang, Xie, Wencheng, Zhao, Guisen

Journal:

Acta Crystallographica Section E Structure Reports Online

Year:

2012

Language:

english

File:

PDF, 456 KB

english, 2012

21

Synthesis and biological evaluation of novel indoline-2,3-dione derivatives as antitumor agents

Li, Pengzhan, Tan, Yanmei, Liu, Guyue, Liu, Yang, Liu, Jianzhen, Yin, Yanzhen, Zhao, Guisen

Journal:

Drug Discoveries & Therapeutics

Year:

2014

Language:

english

File:

PDF, 285 KB

english, 2014

22

New Developments in Diketo-Containing Inhibitors of HIV-1 Integrase

Guisen Zhao, Bentham Science Publisher, Chao Wang, Bentham Science Publisher, Chuan Liu, Bentham Science Publisher, Hongxiang Lou, Bentham Science Publisher, Zhao, Guisen, Wang, Chao, Liu, Chuan, Lou,

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 447 KB

english, 2007

23

Advance in Antitumor Agents Targeting Glutathione-S-Transferase

Zhao, Guisen, Wang, Xiaobing

Journal:

Current Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 120 KB

english, 2006

24

Interaction between variants of two glycosyltransferase genes in IgA nephropathy

Zhu, Li, Tang, Wanwan, Li, Guisen, Lv, Jicheng, Ding, Jiaxiang, Yu, Lei, Zhao, Minghui, Li, Yanda, Zhang, Xuegong, Shen, Yan, Zhang, Hong, Wang, Haiyan

Journal:

Kidney International

Year:

2009

Language:

english

File:

PDF, 218 KB

english, 2009

25

Recent Advances in the Development of Thioredoxin Reductase Inhibitors as Anticancer Agents

Liu, Yang, Li, Yijing, Yu, Shenghui, Zhao, Guisen

Journal:

Current Drug Targets

Year:

2012

Language:

english

File:

PDF, 730 KB

english, 2012

26

Development of anti-angiogenic tyrosine kinases inhibitors: molecular structures and binding modes

Zhang, Jingya, Zhang, Linna, Wang, Yuanyou, Zhao, Guisen

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.48 MB

english, 2016

27

ChemInform Abstract: Thiadiazole - A Promising Structure in Medicinal Chemistry

Li, Yijing, Geng, Jingkun, Liu, Yang, Yu, Shenghui, Zhao, Guisen

Journal:

Year:

2013

File:

PDF, 18 KB

2013

28

Synthesis and Biological Evaluation of Novel σ 1 Receptor Ligands for Treating Neuropathic Pain: 6-Hydroxypyridazinones

Cao, Xudong, Chen, Yin, Zhang, Yifang, Lan, Yu, Zhang, Juecheng, Xu, Xiangqing, Qiu, Yinli, Zhao, Song, Liu, Xin, Liu, Bi-Feng, Zhang, Guisen

Journal:

Journal of Medicinal Chemistry

Year:

2016

Language:

english

File:

PDF, 1.93 MB

english, 2016

29

Preparation and Application of Modified VEGFR-2 Cell Membrane Chromatographic Separation System

Wang, Ying, Fang, Simeng, Zhao, Guisen, Wang, Weihong, Zhao, Zhongxi

Journal:

Chromatographia

Year:

2016

Language:

english

File:

PDF, 1.19 MB

english, 2016

30

Recent Developments in Androgen Receptor Antagonists

Ran, Fansheng, Xing, Hualu, Liu, Yang, Zhang, Daoguang, Li, Pengzhan, Zhao, Guisen

Journal:

Archiv der Pharmazie

Year:

2015

Language:

english

File:

PDF, 1.64 MB

english, 2015

31

Discovery of novel androgen receptor antagonists

Liu, Jianzhen, Liu, Bo, Guo, Guangzhu, Jing, Yongkui, Zhao, Guisen

Journal:

Anti-Cancer Drugs

Year:

2015

Language:

english

File:

PDF, 906 KB

english, 2015

32

Discovery of 4-(Piperazin-1-yl)-7 H -pyrrolo[2,3-d]pyrimidine Derivatives as Akt Inhibitors

Liu, Yang, Yin, Yanzhen, Zhang, Jingya, Nomie, Krystle, Zhang, Liang, Yang, Dezhi, Wang, Michael L., Zhao, Guisen

Journal:

Archiv der Pharmazie

Year:

2016

Language:

english

File:

PDF, 584 KB

english, 2016

33

Synthesis and biological evaluation of 3-(4-fluorophenyl)-1H-pyrazole derivatives as androgen receptor antagonists

Guo, Guangzhu, Liu, Jianzhen, Wang, Guanjie, Zhang, Daoguang, Lu, Jinjie, Zhao, Guisen

Journal:

Anti-Cancer Drugs

Year:

2016

Language:

english

File:

PDF, 292 KB

english, 2016

34

ChemInform Abstract: Recent Developments in Androgen Receptor Antagonists

Ran, Fansheng, Xing, Hualu, Liu, Yang, Zhang, Daoguang, Li, Pengzhan, Zhao, Guisen

Journal:

Year:

2015

File:

PDF, 12 KB

2015

35

Design, Synthesis and Evaluation of Novel Akt1 Inhibitors Based on an Indole Scaffold

Yang, Dezhi, Tong, Dongdong, Zhang, Qian, Wang, Yongtao, Sun, Jing, Zhang, Fenghe, Zhao, Guisen

Journal:

Chemical Biology & Drug Design

Year:

2017

Language:

english

File:

PDF, 417 KB

english, 2017

36

Structural optimization elaborates novel potent Akt inhibitors with promising anticancer activity

Liu, Yang, Yin, Yanzhen, Zhang, Zhen, Li, Carrie J., Zhang, Hui, Zhang, Daoguang, Jiang, Changying, Nomie, Krystle, Zhang, Liang, Wang, Michael L., Zhao, Guisen

Journal:

European Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 1.77 MB

english, 2017

37

Discovery of novel 5-methyl-1 H -pyrazole derivatives as potential anti-prostate cancer agents: design, synthesis, molecular modeling and biological evaluation

Zhang, Daoguang, Asnake, Solomon, Zhang, Jingya, Olsson, Per-Erik, Zhao, Guisen

Journal:

Chemical Biology & Drug Design

Year:

2018

Language:

english

File:

PDF, 448 KB

english, 2018

38

Pharmacological characterizations of H05, a novel potent serotonin and noradrenaline reuptake inhibitor with moderate 5-HT2A antagonist activity for anti-depression

Xu, Xiangqing, Wei, Yaqin, Guo, Qiang, Zhao, Song, Liu, Zhiqiang, Xiao, Ting, Liu, Yani, Qiu, Yinli, Hou, Yuanyuan, Zhang, Guisen, Wang, Kewei

Journal:

Journal of Pharmacology and Experimental Therapeutics

Year:

2018

Language:

english

File:

PDF, 2.35 MB

english, 2018

39

Design, synthesis and biological evaluation of AKT inhibitors bearing a piperidin-4-yl appendant

Zhang, Daoguang, Tong, Dongdong, Yang, Dezhi, Sun, Jing, Zhang, Fenghe, Zhao, Guisen

Journal:

Year:

2018

Language:

english

File:

PDF, 1.56 MB

english, 2018

40

Synthesis and Biological Evaluation of σ1 Receptor Ligands Based on Phenyl‐1,2,4‐oxadiazole Derivatives

Cao, Xudong, Yao, Zhongyuan, Dou, Fei, Zhang, Yifang, Qiu, Yinli, Zhao, Song, Xu, Xiangqing, Liu, Xin, Liu, Bi-Feng, Chen, Yin, Zhang, Guisen

Journal:

Chemistry & Biodiversity

Year:

2018

Language:

english

File:

PDF, 4.23 MB

english, 2018

41

Discovery of novel pyrazole derivatives as potential anticancer agents in MCL

Ran, Fansheng, Liu, Yang, Zhang, Daoguang, Liu, Meixia, Zhao, Guisen

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

File:

PDF, 578 KB

2019

42

Discovery of pyrazolopyrimidine derivatives as potent BTK inhibitors with effective anticancer activity in MCL

Ran, Fansheng, Liu, Yang, Liu, Meixia, Zhang, Daoguang, Wang, Peng, Dong, Junze, Tang, Wendi, Zhao, Guisen

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 2.54 MB

english, 2019

43

Protocol of global incidence and progression of age-related macular degeneration

Zhao, Shan, Lan, Xiaowen, Wu, Jingyang, Yue, Song, Zhang, Han, Wu, Qiang, Zhang, Guisen, Liu, Lei

Journal:

Year:

2019

Language:

english

File:

PDF, 172 KB

english, 2019

44

Recent Advance of Akt Inhibitors in Clinical Trials

Guo, Kaiwen, Tang, Wendi, Zhuo, Huijun, Zhao, Guisen

Journal:

ChemistrySelect

Year:

2019

Language:

english

File:

PDF, 2.24 MB

english, 2019

45

Encouraging Effects of Ethacrynic Acid Derivatives Possessing a Privileged ÃŽÂ±, ÃŽÂ²-Unsaturated Carbonyl Structure Scaffold

Dong, Junze, Yang, Dezhi, Zhao, Guisen

Journal:

Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 720 KB

english, 2018

46

Design and synthesis of novel 1-substituted 3-(6-phenoxypyridin-3-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine analogs as selective BTK inhibitors for the treatment of mantle cell lymphoma

Ran, Fansheng, Liu, Yang, Yu, Shengping, Guo, Kaiwen, Tang, Wendi, Chen, Xin, Zhao, Guisen

Journal:

Bioorganic Chemistry

Year:

2019

Language:

english

File:

PDF, 1.27 MB

english, 2019

47

Small molecules targeting HIF-1α pathway for cancer therapy in recent years

Tang, Wendi, Zhao, Guisen

Journal:

Bioorganic & Medicinal Chemistry

Year:

2019

File:

PDF, 807 KB

2019

48

Extensive Investigation of Benzylic N-containing Substituents on the Pyrrolopyrimidine Skeleton as Akt Inhibitors with Potent Anticancer Activity

Liu, Yang, Zhang, Zhen, Ran, Fansheng, Guo, Kaiwen, Chen, Xin, Zhao, Guisen

Journal:

Bioorganic Chemistry

Year:

2020

File:

PDF, 1.42 MB

2020

49

Kidney manifestations of mild, moderate and severe coronavirus disease 2019: a retrospective cohort study

Hong, Daqing, Long, Lin, Wang, Amanda Y, Lei, Yu, Tang, Yun, Zhao, Jia Wei, Song, Xiaofei, He, Yanan, Wen, Ergang, Zheng, Ling, Li, Guisen, Wang, Li

Journal:

Clinical Kidney Journal

Year:

2020

File:

PDF, 407 KB

2020

50

Gender-differentiated metabolic abnormalities of adult zebrafish with zinc pyrithione (ZPT) -induced hepatotoxicity

Zhao, Ye, Meng, Fanrong, Ding, Cunbao, Yu, Yang, Zhang, Guisen, Tzeng, Chimeng

Journal:

Year:

2020

File:

PDF, 2.58 MB

2020